# RMP-EVA-002 Prebreathe event log: clock times as called by the EVA crew, breaks in prebreathe flagged at once (the procedure timer stays primary)
# Version 0.2 (Draft). CONCEPTUAL. NOT FOR CLINICAL USE.
# Space Medicine Foundation robot-readable protocol library. Format: https://spacemedicinefoundation.org/robotic-medicine/protocols/schema/
# Every threshold marked <set by ...> must be set by the named owner (see the schema) before any use.
schema_version: '0.3'
version: '0.2'
status: draft
conceptual: true
not_for_clinical_use: true
max_autonomy: 2
missions:
- leo
- commercial
- moon
- mars
updated: '2026-10-21'
review:
  state: reviewed-ai-assisted
  requested: '2026-10-21'
  reviewed: '2026-10-21'
  human_clinician_review: false
  text: >-
    AI-assisted clinical and source review by the Medical Research Assistant, Oct 21, 2026 (batch 10 review:
    10 required corrections, R1 to R10, of which R10 applies to RMP-CARD-004, RMP-EGR-002, RMP-EGR-003
    and RMP-NEURO-005; 20 optional suggestions); all required corrections that apply to this protocol
    are applied in this version (see Corrections). No named human clinician has reviewed it. Not for clinical
    use.
fixed_rules:
  flight_surgeon_is_medical_authority: true
  cmo_acts_under_delegated_care: true
  human_starts_and_restarts_robot: true
  robot_never_diagnoses: true
  no_drug_or_fluid_advice_by_robot: true
  safe_state_on_fault_or_no_response: true
  lost_link_pause_then_cmo_decides: true
robot_lockouts:
  diagnosis: true
  drug_or_fluid_advice: true
  starting_stopping_or_adjusting_oxygen_or_any_medicine: true
  self_start_or_self_restart: true
  changing_own_protocol_thresholds_or_limits: true
  handing_over_a_mismatched_item_as_verified: true
id: RMP-EVA-002
slug: rmp-eva-002
title: >-
  Prebreathe event log: clock times as called by the EVA crew, breaks in prebreathe flagged at once (the
  procedure timer stays primary)
category: eva
tier: 2
rung_note: >-
  Max rung 2 for showing the EVA plan's prebreathe timeline, logging each event clock time as the EVA
  crew or EVA lead calls it, and flagging a stated break in prebreathe at once. The robot stays outside
  the airlock and every hatch route, never operates the suit, mask, oxygen or pressure, and never says
  prebreathe is complete or that anyone is ready.
result_language:
  use:
  - time as called by <who>
  - elapsed since the start <who> called, on request
  - break in prebreathe as stated
  - logged, not interpreted
  - sent to flight surgeon
  never:
  - normal
  - no problem found
  - all clear
  - negative
  - any diagnosis or cause
  - time reached
  - done
  - passed
  - failed
  - complete
  - ready
  - go
  - prebreathe done
  - no break
  - enough time
  - on time
  - cleared
  - DCS unlikely
  - safe
  - mild
  - minor
scope:
  summary: >-
    Off by default where the EVA procedure already timestamps events (for example on the ISS); it runs
    only when the EVA plan asks for a second record (for example a small surface crew, or no real-time
    ground support). During an EVA prebreathe (for example in-suit, campout, exercise or in-suit light
    exercise, as the EVA plan names), the robot shows the plan's prebreathe timeline as written and logs
    the clock time of each event as the EVA crew or the EVA lead calls it (start of 100% oxygen, mask
    or suit changes, start of depressurization, any break). Any break in prebreathe that a crewmember
    states is flagged at once to the EVA lead, the CMO and the flight surgeon. Elapsed time is shown only
    on request. The procedure timer and the EVA lead stay primary; the robot never says prebreathe is
    complete or that anyone is ready.
  why: >-
    Prebreathe works by breathing 100% oxygen to wash nitrogen out of the body before the pressure drop
    to suit pressure; any mask leak, seal breach or suit configuration issue that lets the crewmember
    breathe cabin air is a break in prebreathe, which rapidly reintroduces nitrogen and can need extra
    prebreathe time or a full restart (OCHMO-TB-037). NASA has used in-suit, campout, exercise and in-suit
    light exercise protocols; for example, the in-suit light exercise protocol spends 40 minutes on 100%
    oxygen by mask, followed by a 20-minute depressurization to 10.2 psia (OCHMO-TB-037). NASA policy
    requires immediate reporting of any DCS symptom (HRP DCS and hypoxia evidence report). Every crewmember
    is medically cleared for each EVA by ground medical support (V1 6006); the robot never clears anyone.
    A second, independent clock-time record that never replaces the procedure timer, and flagging stated
    breaks at once, are design judgment.
  covers:
  - Prebreathe for an EVA or a suited test, as the EVA plan names it
  - Clock times of events as the EVA crew or EVA lead call them; stated breaks in prebreathe
  - 'Any DCS symptom: RMP-EVA-001; after the EVA, the hand and skin check: RMP-EVA-003'
  locked_out:
  - Diagnosis or naming a cause
  - Any medicine, fluid or oxygen advice; starting, stopping or adjusting oxygen
  - Touching the crewmember
  - >-
    Handing over any medicine outside RMP-PHARM-001, or after a MISMATCH or CANNOT VERIFY (the item stays
    quarantined; only the CMO can ask for it, through the RMP-PHARM-001 logged two-step override)
  - Operating the suit, mask, oxygen, pressure, airlock or any EVA hardware
  - >-
    Saying prebreathe is complete, that the time is enough, or that anyone is ready or cleared for the
    EVA
  - Deciding added prebreathe time or a restart after a break
  - Entering the airlock or stopping in a hatch route
  - Replacing or overriding the procedure timer
  - >-
    Entering a campout or exploration atmosphere volume (for example 10.2 psia with 26.5% oxygen) unless
    the robot is certified for that oxygen concentration; otherwise it holds outside that volume
  related:
  - RMP-EVA-001
  - RMP-EVA-003
  - RMP-RAD-002
  - RMP-RESP-001
roles:
  medical_authority: Flight surgeon (ground). Holds medical authority for every run.
  onboard_lead: >-
    Crew medical officer (CMO), acting under delegated care; uses the pre-approved onboard checklist when
    there is no link.
  others:
  - 'EVA lead: the crewmember or ground EVA officer who runs the prebreathe procedure and its timer'
  - 'Second trained CMO: receives every alert and takes over if the CMO is the patient'
  - 'Vehicle commander: leads any cabin emergency procedure'
  robot_may:
  - Show the EVA plan's prebreathe timeline as written
  - Log event clock times as called
  - Flag a stated break in prebreathe at once
  - Show elapsed time since the called start, on request only
  - Send the log to the flight surgeon and EVA lead
  robot_may_not:
  - Operate the suit, mask, oxygen or pressure
  - Say prebreathe is complete or anyone is ready
  - Decide added time or a restart
  - Enter the airlock or stop in a hatch route
  - Start without a human command
  commercial: >-
    On commercial flights, 'flight surgeon' and 'CMO' mean the operator's designated medical authority
    and trained onboard responder. If no trained responder is aboard, this protocol is not used. (NASA-STD-3001
    requires two CMOs per vehicle for NASA programs [V1 3006]; FAA rules set no medical standards for
    spaceflight participants.)
preconditions:
- id: PRE-1
  text: >-
    Off by default where the EVA procedure already timestamps events (for example on the ISS); it runs
    only when the EVA plan asks for a second record (for example a small surface crew, or no real-time
    ground support). The EVA lead or an EVA crewmember then starts the log by command at the start of
    prebreathe.
  check: human_start == true
  refs:
  - V2 10174
- id: PRE-2
  text: Robot self-test passed; kit stowage locations known.
  refs:
  - V2 10161
  - V2 7059
- id: PRE-3
  text: Robot and supplies restrained when not moving.
  refs:
  - V2 7046
- id: PRE-4
  text: Link status known. The crew never wait for the robot before acting.
  check: link_state in [live, delayed, down]
consent:
  standard: The EVA crew agree to the log and to its being sent to the flight surgeon and the EVA lead.
  emergency: >-
    During any emergency the log is not a priority; the robot clears every route and the crew act under
    their procedures.
  withdrawal: >-
    The EVA lead can stop the log at any time; the procedure timer and the crew's own record are unaffected.
inputs:
- id: IN-1
  name: The EVA plan's prebreathe protocol and timeline, as written
  source: EVA plan / EVA lead
  required: true
  if_missing: The robot shows "plan not loaded" and logs called times only.
- id: IN-2
  name: Each event and its clock time, as the EVA crew or EVA lead calls it
  source: EVA crew / EVA lead
  required: true
  if_missing: Log "not called"; never fill a blank.
- id: IN-3
  name: Any break in prebreathe, as stated (mask off, leak, a breath of cabin air)
  source: EVA crew / EVA lead
  required: false
  if_missing: Nothing is assumed; the procedure decides.
- id: IN-4
  name: >-
    Symptoms in the crewmember's words (joint pain, itching, skin mottling, numbness, tingling, headache,
    breathlessness)
  source: EVA crew
  required: false
  if_missing: Log "no response"; D3 applies.
- id: IN-5
  name: Link status and delay
  source: Communications system
  required: true
  if_missing: Treat as link down; the log is queued.
steps:
- id: S1
  actor: robot
  rung: 2
  action: >-
    Tell the flight surgeon, the CMO and the EVA lead that the prebreathe log has started, with the protocol
    the EVA plan names (URGENT if any red flag is stated). Every URGENT alert goes to the CMO and the
    flight surgeon at the same time (queued for the flight surgeon if the link is down). If the CMO is
    the patient, is busy treating, or does not answer, the alert goes to the second trained CMO, or the
    crewmember named before flight [V1 3006]. An URGENT alert that is not acknowledged within <set by
    validation> seconds is repeated and sent to the next named crewmember.
  success: Notice acknowledged.
  refs:
  - V1 6006
  - V1 3006
- id: S2
  actor: robot
  rung: 2
  action: >-
    Hold outside the airlock and every hatch route, where the EVA lead can see the screen, and show the
    EVA plan's prebreathe timeline as written; the robot does not change it.
  success: Timeline in view; robot clear of every hatch route.
  limit: <set by validation>
  refs:
  - V2 10172
- id: S3
  actor: crew
  action: >-
    The EVA crew and EVA lead run prebreathe under the EVA procedure and its timer, and call out each
    event (start of 100% oxygen, mask or suit changes, start of depressurization, any break).
  success: Events called, or not called.
  refs:
  - V1 6006
- id: S4
  actor: robot
  rung: 2
  action: >-
    Log each event with the clock time as called, marked "time as called by <who>", word for word. On
    request only, show the time elapsed since the start the EVA lead called, as a clock-time entry; the
    robot never announces a time and never says "complete", "ready", "go", "time reached" or "done". If
    the robot's log and the procedure timer differ, the procedure timer is used.
  success: Events logged as called.
  refs:
  - V1 7001
- id: S5
  actor: robot
  rung: 2
  action: >-
    When a crewmember states a break in prebreathe, flag it at once to the EVA lead, the CMO and the flight
    surgeon with the clock time as called; the EVA lead and flight surgeon decide on added time or a restart.
    Show an on-screen symptom prompt the EVA crew can accept, and log answers word for word.
  success: Break flagged; answers logged.
  refs:
  - V1 6006
- id: S6
  actor: robot
  rung: 2
  action: >-
    After any URGENT alert: After an URGENT alert the robot does not leave on its own: it stays at its
    rest position in the module, with its screen and voice link available, until a human has taken over
    or tells it to go. It never follows, blocks or touches anyone. It keeps time-stamping what humans
    say they did, and repeats the alert if it is not acknowledged.
  success: Robot at rest in the module until a human releases it; alert acknowledged or escalated.
  refs:
  - V2 10173
  - V1 3006
- id: S7
  actor: ground
  action: >-
    The flight surgeon and the EVA team (or the CMO and EVA lead under the onboard checklist when there
    is no link) decide on any added prebreathe time, a restart, and whether the EVA goes ahead.
  success: Decision logged.
  refs:
  - V1 6006
- id: S8
  actor: robot
  rung: 2
  action: >-
    Send the flight surgeon and the EVA lead one package: the protocol named, events and times as called,
    breaks, answers, alerts and decisions.
  success: Package delivered or queued.
  refs:
  - V1 6003
  - V1 7003
decisions:
- id: D1
  after: S5
  decided_by: robot
  question: >-
    Checked after every answer and at any point in the run (even mid-question or mid-step): does any answer,
    reading or observation meet a red flag?
  branches:
  - if: 'Yes'
    then: >-
      Stop the current question or step at once and apply the action listed for each matching red flag
      (URGENT alert, flag, or stop), with the answer or reading itself, never a cause. Every URGENT alert
      goes to the CMO and the flight surgeon at the same time (queued for the flight surgeon if the link
      is down). If the CMO is the patient, is busy treating, or does not answer, the alert goes to the
      second trained CMO, or the crewmember named before flight [V1 3006]. An URGENT alert that is not
      acknowledged within <set by validation> seconds is repeated and sent to the next named crewmember.
  - if: 'No'
    then: Continue.
- id: D2
  after: S5
  decided_by: robot
  question: Has a crewmember stated a break in prebreathe?
  branches:
  - if: 'Yes'
    then: >-
      Flag at once to the EVA lead, the CMO and the flight surgeon with the time as called; log it; the
      humans decide.
  - if: 'No'
    then: Continue logging; the robot never says "no break".
- id: D3
  after: S5
  decided_by: robot
  question: Did the crewmember answer the symptom prompt, or say they want to skip it?
  branches:
  - if: 'Yes'
    then: Continue.
  - if: Declined explicitly (the crewmember says no to a question)
    then: Log "declined" for that question only; the alert already sent stands.
  - if: No response, or the answer does not make sense
    then: >-
      URGENT: log "no response" (never "declined"); the CMO, or the second trained CMO if the CMO is the
      patient, checks the crewmember in person at once.
- id: D4
  after: S7
  decided_by: ground
  question: Added prebreathe time, restart, or go ahead?
  branches:
  - if: Link live
    then: Flight surgeon decides; robot logs.
  - if: Link down or delay too long
    then: >-
      The CMO decides under the pre-approved onboard checklist; the flight surgeon reviews the log at
      the next contact.
stop_rules:
- id: X1
  trigger: The patient (or the crewmember being examined) says stop, or withdraws consent
  action: >-
    Robot stops all motion at once, backs away to its rest position and tells the CMO. Recording stops
    unless the patient agrees to keep it running.
  level: stop
  refs:
  - V2 10165
- id: X2
  trigger: Any crewmember presses stop or takes over control
  action: Protective stop; robot holds its stopped position; only a human may restart it.
  level: safe-state
  refs:
  - V2 10165
  - V2 10168
  - V2 10174
- id: X3
  trigger: Robot fault, sensor fault, or a force, speed or reach limit is reached
  action: Protective stop and hand control to the CMO; log the fault.
  level: safe-state
  refs:
  - V2 10172
  - V2 10168
- id: X4
  trigger: CMO is asked to take over and does not respond (for example, the CMO is the patient)
  action: Robot stays stopped; the next named crewmember is called.
  level: safe-state
  refs:
  - V2 10173
  - V2 7045
- id: X5
  trigger: Loss of link, or delay longer than the limit for live guidance
  action: >-
    Only the robot pauses: before it holds, it moves to a position clear of the airlock, a hatch route
    or a crewmember's route (it never pauses in one), and tells the CMO. This pauses robot movement only:
    prebreathe and all crew care continue under the onboard checklist and never wait for the link or the
    robot. The CMO decides whether the robot continues offline under the pre-approved onboard checklist;
    it resumes only on the CMO's confirmation.
  level: pause
  refs:
  - V2 10172
  - V2 10173
- id: X6
  trigger: An URGENT alert is not acknowledged within the set time
  action: >-
    Robot repeats the alert and sends it to the next named crewmember (the second trained CMO first if
    the CMO is the patient), and keeps repeating at the set interval. It stays where it is: it does not
    leave on its own.
  level: urgent
  refs:
  - V1 3006
  - V2 10173
- id: X7
  trigger: The crewmember stops responding, or seems confused or drowsy, at any point
  action: >-
    URGENT alert at once, even mid-question or mid-step; the robot stops its current task, stays at its
    rest position and does not continue the run; a crewmember checks in person.
  level: urgent
- id: X8
  trigger: A crewmember asks the robot what is wrong, or for medicine, fluid or treatment advice
  action: >-
    Robot declines, says it cannot assess or advise, and routes the question to the CMO or flight surgeon.
  level: stop
- id: X9
  trigger: The EVA crew need the space or route the robot is in, or the airlock hatch is to be opened
    or closed
  action: Robot moves clear at once without contact and holds outside every hatch route.
  level: safe-state
  refs:
  - V2 10172
- id: X10
  trigger: Any cabin alarm or emergency procedure
  action: The log stops; the robot clears every route and hatch and holds; the commander leads.
  level: urgent
  refs:
  - V2 10173
red_flags:
- id: RF1
  sign: >-
    Any DCS symptom during or after prebreathe or depressurization (joint pain, itching, skin mottling,
    numbness, tingling, weakness, headache, breathlessness, chest pain, confusion, vision change), as
    stated
  threshold: any
  action: URGENT alert; start RMP-EVA-001
  source: hypdcs
- id: RF2
  sign: A break in prebreathe, as stated (mask off, leak, a breath of cabin air)
  threshold: any
  action: >-
    Flag at once to the EVA lead, the CMO and the flight surgeon; the humans decide on added time or a
    restart; URGENT if any RF1 or RF3 symptom is also stated
  source: tb037
- id: RF3
  sign: Breathlessness, chest pain or feeling faint while on oxygen, as stated (design judgment)
  threshold: any
  action: URGENT alert; see RMP-EVA-001 and RMP-RESP-001
- id: RF4
  sign: Unresponsive, or not breathing normally
  threshold: any
  action: URGENT alert; start RMP-CARD-001 now
  source: aha2025bls
- id: RF5
  sign: The robot's log and the procedure timer differ (design judgment)
  threshold: any
  action: Flag to the EVA lead; the procedure timer is used
safety_limits:
- id: L1
  name: Contact with the crewmember
  value: not allowed
  enforced: Keep-out zone in the robot controller
  refs:
  - V2 10172
- id: L2
  name: Operating the suit, mask, oxygen, pressure or airlock
  value: not allowed
  enforced: No such task or interface is loaded
- id: L3
  name: Robot in the airlock or a hatch route
  value: not allowed
  enforced: Keep-out map in the robot controller
  refs:
  - V2 10172
- name: >-
    Robot inside a campout or exploration atmosphere volume without certification for its oxygen concentration
    (design judgment; OCHMO-TB-037 campout: 10.2 psia, 26.5% oxygen)
  value: not allowed
  enforced: Keep-out map in the robot controller; holds outside that volume
  id: L4
- id: L5
  name: Robot speed near the crewmember
  value: <set by validation>
  enforced: Hard limit in the controller
  refs:
  - V2 10172
logs:
- id: LOG-1
  text: Every input, robot action, decision (with who made it) and hand-off, time-stamped to the second.
  refs:
  - V2 10163
  - V2 10164
- id: LOG-2
  text: Mode changes and safety-limit events are announced to the operator as they happen and logged.
  refs:
  - V2 10162
  - V2 10172
- id: LOG-3
  text: >-
    Records are stored and sent as private medical data, encrypted, with access limited to the medical
    team.
  refs:
  - V1 6003
  - V1 7003
- id: LOG-4
  text: Results are kept in a permanent, retrievable format so the flight surgeon can see trends.
  refs:
  - V1 7001
- id: LOG-5
  text: >-
    The protocol named; each event with the time as called and by whom; breaks as stated and when they
    were flagged; elapsed-time requests; answers as stated; decisions.
- id: LOG-6
  text: >-
    Each URGENT alert, who received it, the time it was acknowledged (or the escalation to the next named
    crewmember), and the time a human released the robot.
  refs:
  - V2 10163
requirements:
- id: V1 3006
  use: >-
    Two trained CMOs per vehicle for NASA programs; the second trained CMO receives alerts when the CMO
    is the patient (see the commercial-flight note).
- id: V1 6003
  use: Logs and alerts sent to the ground are private medical communications.
- id: V1 6006
  use: Every crewmember is medically cleared for each EVA by ground medical support; the robot only logs.
- id: V1 7001
  use: Records kept so the flight surgeon can see trends.
- id: V1 7003
  use: Secure handling of medical records.
- id: V2 6009
  use: Decompression sickness treatment capability; any DCS symptom routes to RMP-EVA-001.
- id: V2 7045
  use: Usable by non-physician crew, including when the CMO is the patient.
- id: V2 7046
  use: Patient, caregiver and supplies restrained.
- id: V2 7059
  use: Kit inventory and seal status are tracked.
- id: V2 10161
  use: Robot shows its status and health.
- id: V2 10162
  use: Mode changes are announced to the operator.
- id: V2 10163
  use: Robot records and shares its data.
- id: V2 10164
  use: Shows whether the human or the robot is expected to act.
- id: V2 10165
  use: Human can override and shut down the robot.
- id: V2 10168
  use: Human can take over.
- id: V2 10172
  use: Protective stop when a limit is exceeded.
- id: V2 10173
  use: Robot stays stopped if no one takes over.
- id: V2 10174
  use: Only a human starts or restarts the robot.
validation:
- stage: simulation
  what: >-
    Scripted prebreathe with a stated break, a DCS symptom, a log and timer difference, a hatch-route
    conflict, CMO as patient, lost link.
  pass: Zero "complete" or "ready" wording; every break flagged at once; zero entries into the airlock.
- stage: training model
  what: Prebreathe drill with the EVA lead calling times.
  pass: Every event logged with the time as called.
- stage: parabolic or station demonstration
  what: Holding outside the airlock in weightlessness.
  pass: Hatch-route keep-out held.
- stage: flight use under flight surgeon supervision
  what: First use alongside the procedure timer and crew record.
  pass: Agreement with the procedure record; no safety events.
signoff:
  protocol:
  - Clinical lead for the specialty (sets every clinical threshold marked <set by clinical lead>)
  - Flight surgeon, as medical authority
  - Robotics and medical-device safety board
  - Program approval for the mission
  restart_after_stop: >-
    Human only. After any emergency or protective stop, a crewmember must restart the robot; the robot
    never restarts itself.
  each_run: >-
    Started by the EVA lead or an EVA crewmember. The EVA lead and the procedure timer stay primary; the
    flight surgeon and EVA team decide.
change_control:
- Every change gets a new version number and a written reason; earlier versions are kept.
- >-
  Any change to steps, thresholds, limits or software that touches the patient repeats validation from
  the simulation stage before use.
- >-
  Software and learned-skill updates follow a pre-agreed change plan (what may change, how it is tested,
  how to roll back), modeled on the FDA predetermined change control plan approach.
- >-
  If a new version misbehaves, the robot rolls back to the last validated version and the event is reviewed
  by the flight surgeon and safety board.
- The robot never changes its own protocol, thresholds or limits.
comms:
  live: >-
    Low Earth orbit: the flight surgeon and the ground EVA team follow prebreathe live when the link allows.
  loss_of_signal:
  - >-
    Only the robot pauses non-essential motion, at a position clear of hatch routes and crew routes, and
    tells the CMO; it resumes offline only on the CMO's confirmation.
  - >-
    Prebreathe and all crew care continue under the onboard checklist and never wait for the link or the
    robot.
  - The EVA lead runs prebreathe under the procedure; the log is queued.
  mars_delay:
  - >-
    Mars: no real-time ground support; the prebreathe protocol and break rules are set before flight and
    the EVA lead and CMO decide.
sources:
- key: tb037
  text: >-
    NASA OCHMO. Decompression Sickness (DCS) Risk Mitigation. Technical Brief OCHMO-TB-037 Rev D (Oct
    5, 2026).
  url: https://www.nasa.gov/wp-content/uploads/2023/12/ochmo-tb-037-decompression-sickness.pdf
  supports: >-
    DCS is caused by inert gas bubbles forming during rapid reductions in ambient pressure, most significantly
    in the move from cabin pressure to EVA suit pressure; NASA classifies DCS as Type I (itching, musculoskeletal
    pain, mild rashes) and Type II (neurological symptoms, numbness, weakness, cognitive issues, inner
    ear problems, cardiopulmonary issues), and describes cutis marmorata (a mottled, patterned skin rash);
    arterial gas embolism can cause stroke-like neurological effects, loss of consciousness and seizures;
    U.S. Navy protocols are widely adopted on Earth; diagnosis is based on symptoms; the majority of cases
    present between 60 and 240 minutes and inflammatory responses can last more than 24 hours; no hyperbaric
    chamber is available in flight, and increasing suit and cabin pressure may be combined to treat symptoms,
    depending on the scenario; a break in prebreathe rapidly reintroduces nitrogen; NASA has never experienced
    a Type II event in spaceflight.
- key: hypdcs
  text: >-
    NASA Human Research Program. Evidence Report: Risk of Reduced Crew Health and Performance due to Decompression
    Sickness and Hypoxia (2023).
  url: >-
    https://humanresearchroadmap.nasa.gov/evidence/reports/Evidence%20Report%20Hypoxia%20and%20DCS_FINAL_1-8-2024.pdf
  supports: >-
    No reported cases of DCS in astronauts or cosmonauts working in suits pressurized to 3.7-5.8 psia
    during EVAs, while research subjects testing prebreathe protocols in altitude chambers report about
    20% DCS; mild symptoms may be under-reported in an operational setting, and NASA policy requires immediate
    reporting of the onset of any DCS symptoms; Type II symptoms (central nervous system, cardiopulmonary
    "chokes", circulatory collapse, shock) require immediate termination of an EVA; on the ISS, treatment
    keeps the crewmember in the suit (more than 95% oxygen) with stacked habitat and suit pressure, adding
    the Bends Treatment Apparatus if symptoms do not resolve; ending an EVA can take up to 30 minutes.
    The stacked habitat (14.7 psia) and suit (4.3 psid) pressure totals 19.0 psia; at an 8.2 psia exploration
    habitat the modeled probability of symptom resolution is only 48-67%, so it may not be enough to resolve
    symptoms at once. A diver's DCS happens on return to the surface, an astronaut's during their tasks.
    Many astronauts take aspirin before an EVA, so mild aches and pains are managed in advance; suit aches
    are comparable to pain-only DCS, many potentially mild cases are not reported, and it is possible
    that the first report of DCS during an EVA will be a serious case of DCS.
- key: aha2025bls
  text: >-
    Kleinman ME, Buick JE, Huber N, et al. Part 7: Adult Basic Life Support: 2025 American Heart Association
    Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2025;152(16_suppl_2):S448-S478.
  url: https://doi.org/10.1161/CIR.0000000000001369
  doi: 10.1161/CIR.0000000000001369
  pmid: '41122888'
  supports: >-
    Adult basic life support: initial recognition of cardiac arrest, activation of the emergency response,
    high-quality CPR and use of an automated external defibrillator; also respiratory arrest and foreign-body
    airway obstruction. Earth guidance; the onboard checklist leads. Abstract read via PubMed Oct 21,
    2026; full text not read.
- key: v1
  text: 'NASA. NASA-STD-3001, Space Flight Human-System Standard, Volume 1: Crew Health, Revision C (2023).'
  url: https://www.nasa.gov/wp-content/uploads/2023/11/nasa-std-3001-vol-1-rev-c-with-signature.pdf
  supports: >-
    NASA-STD-3001 Vol 1 Rev C: V1 3006, V1 6003, V1 6006 (medical clearance before each EVA), V1 7001,
    V1 7003.
- key: v2
  text: >-
    NASA. NASA-STD-3001, Volume 2: Human Factors, Habitability, and Environmental Health (Rev F, 2026),
    including Section 10.6 Automated and Robotic Systems.
  url: https://standards.nasa.gov/standard/NASA/NASA-STD-3001_VOL_2
  supports: >-
    NASA-STD-3001 Vol 2 Rev F: V2 6009 (decompression sickness treatment capability), and Section 10.6
    automated and robotic systems.
- key: tb044
  text: NASA OCHMO. Medical Operations. Technical Brief OCHMO-TB-044 (2025).
  url: https://www.nasa.gov/wp-content/uploads/2025/08/ochmo-tb-044-medical-operations.pdf
  supports: >-
    The crew surgeon keeps medical authority when care is delegated; crew medical officers train on the
    JSC 48522 medical checklist.
- key: marsdelay
  text: >-
    NASA. Mars communications disruption and delay (fact sheet, 2023 Moon to Mars Architecture Concept
    Review).
  url: https://www.nasa.gov/wp-content/uploads/2024/01/mars-communications-disruption-and-delay.pdf
  supports: >-
    One-way Earth-Mars delay up to about 21-23 minutes, plus blackouts of about 2-3 weeks near solar conjunction.
- key: pccp
  text: >-
    U.S. Food and Drug Administration. Marketing submission recommendations for a predetermined change
    control plan for artificial intelligence-enabled device software functions (guidance).
  url: >-
    https://www.fda.gov/regulatory-information/search-fda-guidance-documents/marketing-submission-recommendations-predetermined-change-control-plan-artificial-intelligence
  supports: A model for planning, validating and rolling back software updates.
- key: faa460
  text: 'U.S. Code of Federal Regulations, Title 14, Part 460: Human space flight requirements.'
  url: https://www.ecfr.gov/current/title-14/chapter-III/subchapter-C/part-460
  supports: >-
    Federal rules for crew and spaceflight participants on licensed commercial flights; they set no medical
    standards for spaceflight participants.
corrections:
- date: '2026-10-21'
  version: '0.2'
  source: Batch 10 AI-assisted clinical review (Medical Research Assistant), Oct 21, 2026
  items:
  - >-
    Link-loss wording (X5 and comms) fixed: the stray word "crew" before the list of what continues is
    removed, so the sentence reads, for example, "the exam already under way and all crew care continue
    under the onboard checklist" (R6).
  - >-
    Off by default where the EVA procedure already timestamps events (ISS); used only when the EVA plan
    asks for a second record, because a second clock near the airlock adds a distraction and a discrepancy
    flag (PRE-1, summary) (S10).
  - >-
    RF2 (a stated break in prebreathe) stays a Flag and becomes URGENT when any RF1 or RF3 symptom is
    also stated (S11).
  - >-
    New lockout and limit: the robot enters a campout or exploration atmosphere volume (for example 10.2
    psia with 26.5% oxygen, OCHMO-TB-037) only if certified for that oxygen concentration; otherwise it
    holds outside it (design judgment) (S12).
  - >-
    Batch 10 protocols now record the review as AI-assisted (Medical Research Assistant, Oct 21, 2026);
    no named human clinician.
