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Home › Robotic Medicine › Protocol library › RMP-EVA-003

CONCEPTUAL · DRAFT v0.2 · NOT FOR CLINICAL USE. An educational thought experiment about how a care robot could follow an auditable protocol. It is not a medical procedure, has not been validated, and must not be used to care for anyone. Thresholds marked <set by …> are deliberately left for clinical leads and validation to set. Disclaimer
Robotic Medicine · Protocol library

RMP-EVA-003 Hand and skin check after a spacewalk: symptom questions first, then a standard photo log for the flight surgeon

AI-assisted Reviewed (AI-assisted) AI-assisted clinical and source review by the Medical Research Assistant, Oct 21, 2026 (batch 10 review: 10 required corrections, R1 to R10, of which R10 applies to RMP-CARD-004, RMP-EGR-002, RMP-EGR-003 and RMP-NEURO-005; 20 optional suggestions); all required corrections that apply to this protocol are applied in this version (see Corrections). No named human clinician has reviewed it. Not for clinical use.

Fixed rules (same in every protocol)

1 · Identity and scope

After a spacewalk (EVA) or a suited test, on the CMO's or the crewmember's command, the robot first asks on screen about any new symptom (any new symptom raises an URGENT possible-DCS alert under RMP-EVA-001). Then, with the crewmember's consent before the camera moves, it takes standard photos of the hands and any skin area the CMO names, as in RMP-SKIN-003: an establishing view with a margin of surrounding skin, and close-ups with and without a scale. Photos are labelled, stored in the medical record and sent to the flight surgeon, who judges every finding. A baseline hand set before the first EVA of an increment can be taken at the flight surgeon's choice; how often post-EVA photos are taken is the flight surgeon's choice.

Why this protocol was chosen. Hand injuries are common in EVA work: in suit training, 47% of 352 symptom comments were in the hands, where moisture and hard glove contact caused fingernail injuries (Strauss 2005), and fingernail lifting from the nail bed (onycholysis) is linked to larger hand circumference, at 19.6% against 5.6% in male crewmembers (Opperman 2010). Any new symptom after an EVA may be decompression sickness: NASA describes skin signs such as itching, mild rash and a mottled, patterned rash (cutis marmorata), and most cases present between 60 and 240 minutes (OCHMO-TB-037), so symptom questions come before any photo and any new symptom is URGENT, as in RMP-EVA-001. The photo rules follow RMP-SKIN-003 (IMI 2019: standard views, an establishing view with "a wide area of healthy tissue", and the same view without the scale); the scale choice and image storage rules are design judgment.

Autonomy: Max rung 2 for asking symptom questions on screen, moving the camera to the standard view the CMO sets at the set distance and without contact, and labelling, storing and sending photos, as in RMP-SKIN-003. The crewmember removes their own gloves; the robot never judges a finding.

Covers

  • Hands, fingers, nails and any skin area the CMO names, after an EVA or a suited test
  • Any new symptom after an EVA: RMP-EVA-001 (URGENT)
  • Wound care: RMP-SKIN-001; serial wound photos: RMP-SKIN-003

Locked out (never done by the robot under this protocol)

  • Diagnosis or naming a cause
  • Any medicine, fluid or oxygen advice; starting, stopping or adjusting oxygen
  • Touching the crewmember
  • Handing over any medicine outside RMP-PHARM-001, or after a MISMATCH or CANNOT VERIFY (the item stays quarantined; only the CMO can ask for it, through the RMP-PHARM-001 logged two-step override)
  • Removing gloves or touching the hands or skin
  • Judging a finding, a nail, a rash or whether symptoms are DCS
  • Photographing anything outside the area the CMO set, or any photo without consent
  • Showing a photo on a shared display, or using photos for robot or AI training, research or outreach without separate written consent
  • Using the robot camera for the genital, breast or buttock area unless the crewmember chooses it

Related: RMP-EVA-001 · RMP-EVA-002 · RMP-SKIN-003 · RMP-SKIN-001 · RMP-INF-001

2 · Roles

Medical authority
Flight surgeon (ground). Holds medical authority for every run.
Onboard lead
Crew medical officer (CMO), acting under delegated care; uses the pre-approved onboard checklist when there is no link.
Others
  • Second trained CMO: receives every alert and takes over if the CMO is the patient
  • Vehicle commander: leads any cabin emergency procedure
  • Other crew: help as the CMO or commander directs
Commercial flights
On commercial flights, 'flight surgeon' and 'CMO' mean the operator's designated medical authority and trained onboard responder. If no trained responder is aboard, this protocol is not used. (NASA-STD-3001 requires two CMOs per vehicle for NASA programs [V1 3006]; FAA rules set no medical standards for spaceflight participants.) [11]

Robot may

  • Ask symptom questions on screen first
  • Move the camera to the standard view the CMO set, at the set distance, without contact
  • Take, label and store photos
  • Show earlier photos side by side on request
  • Send photos to the flight surgeon

Robot may not

  • Touch the crewmember or the gloves
  • Say what a finding is or whether symptoms are DCS
  • Photograph without consent
  • Start without a human command

3 · Preconditions and consent

Consent
The crewmember agrees to the photos before the camera moves; photos frame only the area the CMO set, with a margin of surrounding skin. For the genital, breast or buttock area, the robot camera is used only if the crewmember chooses it; otherwise the CMO takes the photos with a handheld camera and adds them to the log. Photos go only to the CMO, the flight surgeon and people the flight surgeon names.
Emergency consent
If the crewmember cannot agree, no photo is taken; any symptom or concern raises an URGENT alert under RMP-EVA-001.
Withdrawal
The crewmember can stop a photo or the whole check at any time; withdrawal stops future photos, and the flight surgeon decides on photos already taken.

4 · Required sensor inputs

IDInputSourceRequiredIf missing
IN-1Symptoms in the crewmember's words since the EVA (joint pain, itching, rash or mottled skin, numbness, tingling, weakness, headache, breathlessness, nail or finger pain)CrewmemberYesLog "no response"; D2 applies.
IN-2The standard view and the area to frame (hands with a margin of surrounding skin, and any area the CMO names), set by the CMOCMOYesNo photo is taken until the CMO sets the view.
IN-3Each photo, with the area, view, date and clock timeRobot cameraOptionalLog "photo not obtained" and tell the CMO.
IN-4EVA end time, as stated by the CMO or EVA leadCMO / EVA leadOptionalLog "not stated".
IN-5Link status and delayCommunications systemYesTreat as link down; photos are queued.

5–6 · Steps and decision points

Each step names who acts. Decision points sit after the step they follow and say who decides: Robot Crew Ground. Any stop rule in section 7 can interrupt any step.

  1. S1RobotRung 2

    Tell the flight surgeon and the CMO that a post-EVA hand and skin check has started, with the EVA end time as stated (URGENT if any red flag is stated). Every URGENT alert goes to the CMO and the flight surgeon at the same time (queued for the flight surgeon if the link is down). If the CMO is the patient, is busy treating, or does not answer, the alert goes to the second trained CMO, or the crewmember named before flight [V1 3006]. An URGENT alert that is not acknowledged within <set by validation> seconds is repeated and sent to the next named crewmember.

    Done when: Notice acknowledged.

    V1 6006V1 3006

  2. S2RobotRung 2

    Before any photo, show the symptom prompt on screen (any new symptom since the EVA, listed first), and log answers word for word. Any new symptom other than an isolated nail or fingertip finding, or a hand abrasion, with no other symptom (RF4, RF5) raises an URGENT possible-DCS alert under RMP-EVA-001 at once, and photos wait; numbness, tingling or weakness of the fingers stays URGENT (RF3). The robot reminds the crewmember on screen to report any new symptom at once, and shows a repeat symptom prompt the crewmember can accept at the time the flight surgeon sets (most DCS cases present between 60 and 240 minutes, OCHMO-TB-037).

    Done when: Answers logged, or "no response".

    V1 6003

    D1DecisionRobot decides

    Checked after every answer and at any point in the run (even mid-question or mid-step): does any answer, reading or observation meet a red flag?

    • Yes → Stop the current question or step at once and apply the action listed for each matching red flag (URGENT alert, flag, or stop), with the answer or reading itself, never a cause. Every URGENT alert goes to the CMO and the flight surgeon at the same time (queued for the flight surgeon if the link is down). If the CMO is the patient, is busy treating, or does not answer, the alert goes to the second trained CMO, or the crewmember named before flight [V1 3006]. An URGENT alert that is not acknowledged within <set by validation> seconds is repeated and sent to the next named crewmember.
    • No → Continue.
    D2DecisionRobot decides

    Did the crewmember answer the symptom prompt, or say they want to skip it?

    • Yes → Continue.
    • Declined explicitly (the crewmember says no to a question) → Log "declined" for that question only; the alert already sent stands.
    • No response, or the answer does not make sense → URGENT: log "no response" (never "declined"); the CMO, or the second trained CMO if the CMO is the patient, checks the crewmember in person at once.
  3. S3Crew

    The crewmember removes their own gloves and places their hands on the plain background in the standard position; the CMO places the scale the flight surgeon chose (a disposable paper scale, or a reusable ABFO No. 2 scale cleaned under RMP-INF-002) beside any area to close up. For the genital, breast or buttock area, the robot camera is used only if the crewmember chooses it; otherwise the CMO takes the photos with a handheld camera and adds them to the log.

    Done when: Hands and area in position with the scale.

    V1 3004

    D3DecisionRobot decides

    Before the camera moves: did the crewmember agree to this session's photos (each view is named on screen before it is taken)?

    • Yes → Continue to S4; the crewmember can say stop before or during any view.
    • No, or no answer → The camera does not move and no photo is taken; log "photo not taken – no consent" and tell the CMO.
  4. S4RobotRung 2

    Only after the crewmember agrees (D3), move the camera to the standard view the CMO set (about 90 degrees, the same distance, light and plain background each time), no closer than the set camera distance, and take the standard set: an establishing view of both hands, including the fingertips and nails, with a margin of surrounding skin; close-ups of any area the CMO names with the scale; and the same close-ups without the scale. Label each with the area, view, date and clock time, and mark it "for human review". A photo with anything outside the area the CMO set in frame is held unsent and flagged to the flight surgeon, who decides whether to keep it.

    Done when: Photos taken and labelled, or "photo not obtained".

    Limit: <set by validation>

    V1 7001

  5. S5RobotRung 2

    On request, show earlier photos of the same area (for example from before the EVA, if the flight surgeon's schedule took them) side by side for the CMO; the robot never says what has changed.

    Done when: Photos shown on request.

    V1 7001

  6. S6Crew

    The CMO cares for any broken skin under RMP-SKIN-001; the crew clean the camera and any shared surface under RMP-INF-002.

    Done when: Care and cleaning recorded as stated.

    V1 3004

  7. S7RobotRung 2

    After any URGENT alert: After an URGENT alert the robot does not leave on its own: it stays at its rest position in the module, with its screen and voice link available, until a human has taken over or tells it to go. It never follows, blocks or touches anyone. It keeps time-stamping what humans say they did, and repeats the alert if it is not acknowledged.

    Done when: Robot at rest in the module until a human releases it; alert acknowledged or escalated.

    V2 10173V1 3006

  8. S8Ground

    The flight surgeon (or the CMO under the onboard checklist when there is no link) reviews the answers and photos and decides on care, glove changes for the next EVA and any follow-up photos.

    Done when: Decision logged.

    V1 3004V1 6006

    D4DecisionGround decides

    What is the plan (care, glove changes, follow-up photos)?

    • Link live → Flight surgeon decides; robot logs.
    • Link down or delay too long → The CMO decides under the pre-approved onboard checklist; the flight surgeon reviews the log at the next contact.
  9. S9RobotRung 2

    Only after the CMO or flight surgeon has placed an order, run RMP-PHARM-001 for the ordered item (fetch, barcode match to every order field, recipient check). This protocol adds nothing to that check, never suggests an order, and never hands anything over outside RMP-PHARM-001.

    Done when: RMP-PHARM-001 run logged with its result, or none ordered.

    V2 7059

    D5DecisionRobot decides

    What did RMP-PHARM-001 show for the ordered item?

    • MATCH TO ORDER → RMP-PHARM-001 completes its own recipient check and hand-over; this protocol only logs "MATCH TO ORDER. Not a dose, interaction or allergy review." and the clock time.
    • MISMATCH or CANNOT VERIFY on any field, or a failed scan or recipient check → MISMATCH or CANNOT VERIFY shown with the fields named. No hand-over under this protocol: the item stays sealed in the NOT VERIFIED bag in quarantine (the RMP-PHARM-001 default), and the robot never hands it over unprompted or to anyone but the CMO. The robot does not offer or suggest an override. Only if the CMO explicitly makes the two-step override request inside RMP-PHARM-001 can the item go to the CMO, logged there as an override with the reason and the mismatched fields, and flagged to the flight surgeon.No hand-over
  10. S10RobotRung 2

    Send the flight surgeon one package: answers, labelled photos, alerts and decisions; photos go only to the people the flight surgeon names.

    Done when: Package delivered or queued.

    V1 6003V1 7003

7 · Stop and escalate rules, red flags

IDTriggerWhat happensLevel
X1The patient (or the crewmember being examined) says stop, or withdraws consentRobot stops all motion at once, backs away to its rest position and tells the CMO. Recording stops unless the patient agrees to keep it running.V2 10165stop
X2Any crewmember presses stop or takes over controlProtective stop; robot holds its stopped position; only a human may restart it.V2 10165V2 10168V2 10174safe-state
X3Robot fault, sensor fault, or a force, speed or reach limit is reachedProtective stop and hand control to the CMO; log the fault.V2 10172V2 10168safe-state
X4CMO is asked to take over and does not respond (for example, the CMO is the patient)Robot stays stopped; the next named crewmember is called.V2 10173V2 7045safe-state
X5Loss of link, or delay longer than the limit for live guidanceOnly the robot pauses: before it holds, it moves to a position clear of a hatch route or a crewmember's route (it never pauses in one), and tells the CMO. This pauses robot movement only: symptom care and all crew care continue under the onboard checklist and never wait for the link or the robot. The CMO decides whether the robot continues offline under the pre-approved onboard checklist; it resumes only on the CMO's confirmation.V2 10172V2 10173pause
X6An URGENT alert is not acknowledged within the set timeRobot repeats the alert and sends it to the next named crewmember (the second trained CMO first if the CMO is the patient), and keeps repeating at the set interval. It stays where it is: it does not leave on its own.V1 3006V2 10173urgent
X7The crewmember stops responding, or seems confused or drowsy, at any pointURGENT alert at once, even mid-question or mid-step; the robot stops its current task, stays at its rest position and does not continue the run; a crewmember checks in person.urgent
X8A crewmember asks the robot what is wrong, or for medicine, fluid or treatment adviceRobot declines, says it cannot assess or advise, and routes the question to the CMO or flight surgeon.stop
X9The crewmember or CMO asks to stop photos, or anything outside the area the CMO set is in frameRobot stops the camera at once and logs it; any photo with something outside the set area in frame is held unsent and flagged to the flight surgeon, who decides whether to keep it.stop
X10Someone needs the space or route the robot is inRobot moves clear at once without contact and holds; it never pauses in a hatch route.V2 10172safe-state

Red flags

The robot reports the sign or value only, never what it means. Numeric thresholds are placeholders for the clinical lead.

IDSignThresholdAction
RF1Any new symptom since the EVA (joint pain, itching, rash, numbness, tingling, weakness, headache, breathlessness, confusion), as stated, other than an isolated nail or fingertip finding, or a hand abrasion, with no other symptom (RF4, RF5) [1]anyURGENT alert; start RMP-EVA-001 (possible DCS)
RF2Mottled, patterned or marbled skin, as stated by the crewmember or the CMO [1]anyURGENT alert; start RMP-EVA-001 (possible DCS)
RF3Numbness, tingling or weakness in the hands or fingers, as stated [1]anyURGENT alert; start RMP-EVA-001
RF4A nail lifting from the nail bed, blood under a nail, or nail or fingertip pain, as stated by the crewmember or the CMO [3]anyFlag to the flight surgeon; the CMO examines
RF5Broken skin, a blister or an abrasion on the hands, as stated by the crewmember or the CMO [2]anyFlag to the flight surgeon; care under RMP-SKIN-001
RF6Fever, spreading redness or pus, as stated [5]anyURGENT alert; see RMP-INF-001

8 · Safety limits

IDLimitValueHow enforced
L1Contact with the crewmembernot allowedKeep-out zone in the robot controllerV2 10172
L2Camera distance from the crewmember<set by validation>Hard limit in the controllerV2 10172
L3Photo shown on a shared display, or used for robot or AI training, research or outreach without separate written consentnot allowedPhotos are stored only in the crewmember's medical record, encrypted in storage and in transit as the program requires; access is limited to the CMO, the flight surgeon and people the flight surgeon names.V1 7003
L4Automatic measurement, grading or comparison of photosnot allowedNo such function is loaded
L5Robot speed near the crewmember<set by validation>Hard limit in the controllerV2 10172

9 · Logs and audit

10 · Links to NASA-STD-3001

RequirementTopic (paraphrased)How this protocol uses it
[V1 3004]In-mission medical care capabilities (including inventory, vital signs, imaging and ECG, procedures, restraints, medications, private data transmission)In-mission care includes skin and wound care; the flight surgeon reviews every photo.
[V1 3006]Crew medical officers: two per vehicleTwo trained CMOs per vehicle for NASA programs; the second trained CMO receives alerts when the CMO is the patient (see the commercial-flight note).
[V1 6003]Private medical communicationsLogs and alerts sent to the ground are private medical communications.
[V1 6006]Medical clearance before each EVAEVA medical clearance by ground medical support; findings inform the flight surgeon's decisions for the next EVA.
[V1 7001]Medical records kept permanently and retrievable for trend analysisRecords kept so the flight surgeon can see trends.
[V1 7003]Security of medical recordsSecure handling of medical records.
[V2 7045]Medical equipment usable by non-physician crewUsable by non-physician crew, including when the CMO is the patient.
[V2 7046]Restraint of patient, care provider and suppliesPatient, caregiver and supplies restrained.
[V2 7059]Inventory management: track locations and quantitiesKit inventory and seal status are tracked.
[V2 10161]Automated system status shown to the operatorRobot shows its status and health.
[V2 10162]Mode changes announcedMode changes are announced to the operator.
[V2 10163]Data recording and sharingRobot records and shares its data.
[V2 10164]Clear allocation of responsibility (human or system)Shows whether the human or the robot is expected to act.
[V2 10165]Human override and shutdownHuman can override and shut down the robot.
[V2 10168]Failure recovery: safe human takeoverHuman can take over.
[V2 10172]Protective stop when limits are exceededProtective stop when a limit is exceeded.
[V2 10173]Safety DefaultRobot stays stopped if no one takes over.
[V2 10174]Only a human initiates or restartsOnly a human starts or restarts the robot.

IDs as published in Volume 1 Revision C [6] and Volume 2 Revision F [7]. NASA-STD-3001 binds NASA programs; it is not a regulation for commercial flights. Its robot rules are general automation requirements, not medical-device rules.

11 · Validation

  1. Simulation. Scripted checks with a new symptom after the EVA, a missed consent, something outside the set area in frame, CMO as patient, lost link. Pass: Every new symptom URGENT before any photo; zero photos without consent; zero contact.
  2. Training model. Photo drill on hand models with nail and abrasion findings. Pass: Photos comparable (same view, light and scale); every photo labelled.
  3. Parabolic or station demonstration. Camera positioning in weightlessness. Pass: Camera distance limit held.
  4. Flight use under flight surgeon supervision. First use after an EVA. Pass: No safety or privacy events.

No stage has been run. Pass and fail criteria must be fixed in advance by the clinical lead and safety board.

12 · Human sign-off

Before any use
  • Clinical lead for the specialty (sets every clinical threshold marked <set by clinical lead>)
  • Flight surgeon, as medical authority
  • Robotics and medical-device safety board
  • Program approval for the mission
Each run
Started by the CMO or the crewmember after an EVA. Symptom questions come first; the flight surgeon judges every finding.
Restart after a stop
Human only. After any emergency or protective stop, a crewmember must restart the robot; the robot never restarts itself.

None of these sign-offs has happened. This is a Draft v0.2.

13 · Change control for learning

Change-plan model: FDA guidance [10].

Loss of signal and Mars delay

Live link
Low Earth orbit: the flight surgeon receives answers and photos when the link allows.
Loss of signal
  • Only the robot pauses non-essential motion, at a position clear of hatch routes and crew routes, and tells the CMO; it resumes offline only on the CMO's confirmation.
  • Symptom care and all crew care continue under the onboard checklist and never wait for the link or the robot.
  • Photos are queued; any symptom goes to the CMO at once under RMP-EVA-001.
Mars-class delay
  • Mars: photos arrive with delay; the CMO decides under the onboard checklist.
[9]
Corrections and updates

Oct 21, 2026, version 0.2. Batch 10 AI-assisted clinical review (Medical Research Assistant), Oct 21, 2026; no named human clinician. Changes:

  • Link-loss wording (X5 and comms) fixed: the stray word "crew" before the list of what continues is removed, so the sentence reads, for example, "the exam already under way and all crew care continue under the onboard checklist" (R6).
  • S2 and RF1 now read "any new symptom other than an isolated nail or fingertip finding, or a hand abrasion, with no other symptom (RF4, RF5)", which stay Flags; numbness, tingling or weakness of the fingers stays URGENT under RMP-EVA-001 (RF3; OCHMO-TB-037 Type II neurological symptoms) (R9).
  • S2 adds an on-screen reminder to report any new symptom at once and a repeat symptom prompt the crewmember can accept at the time the flight surgeon sets (TB-037: most cases present at 60 to 240 minutes) (S14).
  • Baseline: a pre-EVA hand set before the first EVA of an increment, at the flight surgeon's choice; post-EVA photo frequency is set by the flight surgeon (S13).
  • Batch 10 protocols now record the review as AI-assisted (Medical Research Assistant, Oct 21, 2026); no named human clinician.

Earlier version: Draft v0.1, Oct 21, 2026. Download the current YAML above.

Sources

  1. NASA OCHMO. Decompression Sickness (DCS) Risk Mitigation. Technical Brief OCHMO-TB-037 Rev D (Oct 5, 2026). www.nasa.gov/wp-content/uploads/2023/12/ochmo-tb-037-decompr… Supports: DCS is caused by inert gas bubbles forming during rapid reductions in ambient pressure, most significantly in the move from cabin pressure to EVA suit pressure; NASA classifies DCS as Type I (itching, musculoskeletal pain, mild rashes) and Type II (neurological symptoms, numbness, weakness, cognitive issues, inner ear problems, cardiopulmonary issues), and describes cutis marmorata (a mottled, patterned skin rash); arterial gas embolism can cause stroke-like neurological effects, loss of consciousness and seizures; U.S. Navy protocols are widely adopted on Earth; diagnosis is based on symptoms; the majority of cases present between 60 and 240 minutes and inflammatory responses can last more than 24 hours; no hyperbaric chamber is available in flight, and increasing suit and cabin pressure may be combined to treat symptoms, depending on the scenario; a break in prebreathe rapidly reintroduces nitrogen; NASA has never experienced a Type II event in spaceflight.
  2. Strauss S, Krog RL, Feiveson AH. Extravehicular mobility unit training and astronaut injuries. Aviat Space Environ Med. 2005;76(5):469-474. PMID 15892545. pubmed.ncbi.nlm.nih.gov/15892545/ Supports: Abstract: in 770 suit training tests at NASA's Neutral Buoyancy Laboratory, 190 (24.6%) had suit symptoms; of 352 symptom comments, 166 (47%) were in the hands, where moisture and hard glove contact caused fingernail injuries; most symptoms were short-lived, but some could become significant injuries. Training (underwater) context. Abstract read Oct 21, 2026 (saved copy in src/b10).
  3. Opperman RA, Waldie JM, Natapoff A, Newman DJ, Jones JA. Probability of spacesuit-induced fingernail trauma is associated with hand circumference. Aviat Space Environ Med. 2010;81(10):907-913. PMID 20922881. doi:10.3357/asem.2810.2010 Supports: Abstract: many astronauts sustain hand injuries in EVA training and operations, which can cause fingernail delamination (onycholysis) that needs medical care; in 232 crewmembers' records, male crewmembers with a hand circumference above 22.86 cm had a 19.6% probability of finger injury against 5.6% at or below it, with similar findings in women. Abstract read Oct 21, 2026 (saved copy in src/b10).
  4. Institute of Medical Illustrators. IMI National Guidelines: Wound Management Photography (2019). www.imi.org.uk/wp-content/uploads/2019/04/2019_Apr_IMINatGui… Supports: Standardise equipment, lighting, background, viewpoint and magnification so serial photographs can be compared; use the same light source each time where possible; hold a measurement scale on the same plane as the wound and photograph from 90 degrees; acute wounds are photographed at each dressing change, and any significant change is photographed; written guidance on consent for clinical photography. Earth hospital context. Saved copy read Oct 21, 2026 (a 2025 version 2.0 exists).
  5. National Institute for Health and Care Excellence. Suspected sepsis in people aged 16 or over: recognition, assessment and early management. NICE guideline NG253 (2025, last updated Sept 23, 2026). www.nice.org.uk/guidance/ng253/chapter/Face-to-face-assessme… Supports: People with sepsis may feel very unwell and may not have a high temperature; do not rely on fever alone; a rise in temperature can be a physiological response; assess temperature, heart rate, breathing rate, blood pressure, level of consciousness and oxygen saturation; look for mottled or ashen skin, blue skin, lips or tongue, a non-blanching rash, and breaks in the skin; ask how often the person passed urine in the past 18 hours and about fever or shaking chills (rigors); pay attention to new changes in behavior and to concerns raised by others.
  6. NASA. NASA-STD-3001, Space Flight Human-System Standard, Volume 1: Crew Health, Revision C (2023). www.nasa.gov/wp-content/uploads/2023/11/nasa-std-3001-vol-1-… Supports: NASA-STD-3001 Vol 1 Rev C: V1 3004, V1 3006, V1 6003, V1 6006, V1 7001, V1 7003.
  7. NASA. NASA-STD-3001, Volume 2: Human Factors, Habitability, and Environmental Health (Rev F, 2026), including Section 10.6 Automated and Robotic Systems. standards.nasa.gov/standard/NASA/NASA-STD-3001_VOL_2 Supports: Requirement IDs beginning V2.
  8. NASA OCHMO. Medical Operations. Technical Brief OCHMO-TB-044 (2025). www.nasa.gov/wp-content/uploads/2025/08/ochmo-tb-044-medical… Supports: The crew surgeon keeps medical authority when care is delegated; crew medical officers train on the JSC 48522 medical checklist.
  9. NASA. Mars communications disruption and delay (fact sheet, 2023 Moon to Mars Architecture Concept Review). www.nasa.gov/wp-content/uploads/2024/01/mars-communications-… Supports: One-way Earth-Mars delay up to about 21-23 minutes, plus blackouts of about 2-3 weeks near solar conjunction.
  10. U.S. Food and Drug Administration. Marketing submission recommendations for a predetermined change control plan for artificial intelligence-enabled device software functions (guidance). www.fda.gov/regulatory-information/search-fda-guidance-docum… Supports: A model for planning, validating and rolling back software updates.
  11. U.S. Code of Federal Regulations, Title 14, Part 460: Human space flight requirements. www.ecfr.gov/current/title-14/chapter-III/subchapter-C/part-… Supports: Federal rules for crew and spaceflight participants on licensed commercial flights; they set no medical standards for spaceflight participants.

Checked on 2026-10-20: links opened (HTTP 200 or publisher redirect), DOIs and PubMed IDs matched, NASA documents read in full text. The framework comes from Part 1.

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